9RYA

RAPTA-3MB (Ruthenium[II]-1,3,5-trimethylbenzene-phosphaadamantane) cancer drug binding to the nucleosome core

This is a non-PDB format compatible entry.

Summary for 9RYA

• Entry DOI: 10.2210/pdb9rya/pdb
• Descriptor: Histone H3.2, Histone H4, Histone H2A, ... (9 entities in total)
• Functional Keywords: chromatin; nucleosome; histone; drug binding; cancer drug; antimetastasis drug; metal-based compound; rapta; rapta-3mb; ruthenium agent; drug adduct, dna binding protein
• Biological source: Xenopus laevis (African clawed frog); More
• Total number of polymer chains: 10
• Total formula weight: 199202.46

Authors

Adhireksan, Z.,Davey, C.A. (deposition date: 2025-07-14, release date: 2026-07-22)

• Primary citation: Davey, C.A.; RAPTA-3MB (Ruthenium[II]-1,3,5-trimethylbenzene-phosphaadamantane) cancer drug binding to the nucleosome core; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)