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9RXV

RAPTA-T (Ruthenium[II]-toluene-phosphaadamantane) cancer drug binding to the nucleosome core

This is a non-PDB format compatible entry.
Summary for 9RXV
Entry DOI10.2210/pdb9rxv/pdb
Related5DNM
DescriptorHistone H3.2, Histone H4, Histone H2A, ... (9 entities in total)
Functional Keywordschromatin; nucleosome; histone; drug binding; cancer drug; antimetastasis drug; metal-based compound; rapta; rapta-t; ruthenium agent; drug adduct, dna binding protein
Biological sourceXenopus laevis (African clawed frog)
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Total number of polymer chains10
Total formula weight199138.29
Authors
Adhireksan, Z.,Muhammad, R.,Davey, C.A. (deposition date: 2025-07-13, release date: 2026-07-22)
Primary citationDavey, C.A.
RAPTA-T (Ruthenium[II]-toluene-phosphaadamantane) cancer drug binding to the nucleosome core
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.6 Å)
Structure validation

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