9RX7

VPS34-CI bound to NRBF2 MIT domain (residues 1-79)

Summary for 9RX7

• Entry DOI: 10.2210/pdb9rx7/pdb
• EMDB information: 54360
• Descriptor: Phosphatidylinositol 3-kinase catalytic subunit type 3, Phosphoinositide 3-kinase regulatory subunit 4, Beclin-1, ... (9 entities in total)
• Functional Keywords: lipid kinase, gtpase, kinase, autophagy, signaling protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 6
• Total formula weight: 429348.24

Authors

Spokaite, S.,Ohashi, Y.,Dessus, A.N.,Bourguet, M.,Williams, R.L. (deposition date: 2025-07-10, release date: 2026-07-22)

• Primary citation: Spokaite, S.,Ohashi, Y.,Dessus, A.N.,Bourguet, M.,Williams, R.L.; When VPS34 complexes double down: Two RAB5s for VPS34-CII, two RAB1s for NRBF2-dimerized VPS34-CI; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.33 Å)