9ROT

Assembly intermediate of human mitochondrial ribosome small subunit bound to METTL15, RBFA, and mtIF2 (State M2.1)

This is a non-PDB format compatible entry.

Replaces:  9IGT

Summary for 9ROT

• Entry DOI: 10.2210/pdb9rot/pdb
• EMDB information: 54130
• Descriptor: 28S ribosomal protein S34, mitochondrial, 28S ribosomal protein S14, mitochondrial, 28S ribosomal protein S15, mitochondrial, ... (41 entities in total)
• Functional Keywords: mitochondrial gene expression, mitoribosome, mitoribosome assembly factors, cryoem, ribosome
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 33
• Total formula weight: 1297587.36

Authors

Khawaja, A.,Singh, V.,Shiriaev, D.I.,Rorbach, J. (deposition date: 2025-06-22, release date: 2026-07-01)

• Primary citation: Singh, V.,Shiriaev, D.,Bilalli, L.,Khawaja, A.,Rorbach, J.; Pseudouridine synthase PUS1 and initiation factor mtIF2 are human mitoribosomal small subunit assembly factors; Nat Commun, 17:5564-, 2026; DOI: 10.1038/s41467-026-74700-x

Experimental method

ELECTRON MICROSCOPY (4.3 Å)