9RKW

Insulin receptor ectodomain in complex with s661 insulin mimetic

Summary for 9RKW

• Entry DOI: 10.2210/pdb9rkw/pdb
• EMDB information: 54023
• Descriptor: Insulin receptor, s661 peptide (3 entities in total)
• Functional Keywords: complex, ir, s661, membrane protein, antagonist, insulin mimetic
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 188423.48

Authors

Polak, M.,Novacek, J.,Jiracek, J. (deposition date: 2025-06-15, release date: 2026-06-24)

• Primary citation: Polak, M.,Pinkas, M.,Hernandez, M.S.G.,Fabre, B.,Lubos, M.,Zakova, L.,Grzybek, M.,Schaefer, I.B.,Coskun, U.,Jiracek, J.,Novacek, J.; Antagonistic insulin mimetics lock the insulin receptor in an alternative apo-state; To Be Published,

Experimental method

ELECTRON MICROSCOPY (8 Å)