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9RKD

Insulin receptor ectodomain in apo-conformation

Summary for 9RKD
Entry DOI10.2210/pdb9rkd/pdb
EMDB information54015
DescriptorIsoform Short of Insulin receptor, Insulin receptor (2 entities in total)
Functional Keywordscomplex, ir, apo-form, membrane protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains4
Total formula weight201957.13
Authors
Polak, M.,Novacek, J.,Jiracek, J. (deposition date: 2025-06-13, release date: 2026-06-24)
Primary citationPolak, M.,Pinkas, M.,Hernandez, M.S.G.,Fabre, B.,Lubos, M.,Zakova, L.,Grzybek, M.,Schaefer, I.B.,Coskun, U.,Jiracek, J.,Novacek, J.
Antagonistic insulin mimetics lock the insulin receptor in an alternative apo-state
To Be Published,
Experimental method
ELECTRON MICROSCOPY (6 Å)
Structure validation

255615

PDB entries from 2026-06-24

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