9RJ4

Bub1 kinase domain in complex with inhibitor LEI221

This is a non-PDB format compatible entry.

Summary for 9RJ4

• Entry DOI: 10.2210/pdb9rj4/pdb
• Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, 5-chloranyl-1-[[4-ethoxy-2,6-bis(fluoranyl)phenyl]methyl]-3-[5-methoxy-4-(1H-pyrazol-4-ylamino)pyrimidin-2-yl]pyridin-2-one, GLYCEROL, ... (5 entities in total)
• Functional Keywords: kinase, inhibitor, cell cycle
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 85057.17

Authors

Konijnenberg, M.J.,Ahmad, M.U.D.,Perrakis, A. (deposition date: 2025-06-12, release date: 2026-06-24)

• Primary citation: Konijnenberg, M.J.; Bub1 kinase domain in complex with inhibitor LEI221; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.85 Å)