9RJ2

Bub1 kinase domain in complex with covalent inhibitor BM047

This is a non-PDB format compatible entry.

Summary for 9RJ2

• Entry DOI: 10.2210/pdb9rj2/pdb
• Descriptor: Mitotic checkpoint serine/threonine-protein kinase BUB1, GLYCEROL, (2~{R})-~{N}-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-prop-2-ynoxy-quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, ... (4 entities in total)
• Functional Keywords: kinase, covalent inhibitor, cell cycle
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 84722.78

Authors

Konijnenberg, M.J.,Ahmad, M.U.D.,Perrakis, A. (deposition date: 2025-06-12, release date: 2026-06-24)

• Primary citation: Konijnenberg, M.J.; Bub1 kinase domain in complex with covalent inhibitor BM047; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)