9RIW
Population A fibril generated from the Heterotypic interaction of Abeta40 and Medin.
Summary for 9RIW
| Entry DOI | 10.2210/pdb9riw/pdb |
| EMDB information | 54007 |
| Descriptor | Amyloid-beta protein 40 (1 entity in total) |
| Functional Keywords | amyloid beta 40, aggregation, neurodegeneration, medin, protein fibril |
| Biological source | Homo sapiens (human) |
| Total number of polymer chains | 8 |
| Total formula weight | 34686.82 |
| Authors | Pradhan, B.,Kumar, S.T.,Wagner, J.,Gallardo, R.,Orlando, G.,Vleeschouwer, M.D.,Madine, J.,Louros, N.,Neher, J.,Schymkowitz, J.,Rousseau, F. (deposition date: 2025-06-11, release date: 2026-04-08) |
| Primary citation | Pradhan, B.,Kumar, S.T.,Wagner, J.,Gallardo, R.,Orlando, G.,Vleeschouwer, M.D.,Madine, J.,Louros, N.,Neher, J.,Schymkowitz, J.,Rousseau, F. In Vitro Co-Aggregation with medin Induces an Abeta42-Like Polymorph of Abeta40 Fibrils. To Be Published, |
| Experimental method | ELECTRON MICROSCOPY (3.1 Å) |
Structure validation
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