9RGP

SsCl at pH 9 + IVM - Opened

Summary for 9RGP

• Entry DOI: 10.2210/pdb9rgp/pdb
• EMDB information: 53953
• Descriptor: pH gated chloride channel, (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, CHLORIDE ION (3 entities in total)
• Functional Keywords: ion channel, plgic, ph-sensitive channel, ivermectin, membrane protein
• Biological source: Sarcoptes scabiei
• Total number of polymer chains: 5
• Total formula weight: 182231.03

Authors

Kleiz-Ferreira, J.,Brams, M.,Harrison, P.J.,Nys, M.,Gallagher, C.,Donze, Y.,Quigley, A.,Bertrand, D.,Ulens, C. (deposition date: 2025-06-06, release date: 2026-03-18)

• Primary citation: Kleiz-Ferreira, J.,Brams, M.,Harrison, P.J.,Nys, M.,Gallagher, C.,Donze, Y.,Quigley, A.,Bertrand, D.,Ulens, C.; SsCl at pH 9 + IVM - Opened; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.65 Å)