9RGE

CryoEM structure of human alpha1beta3gamma2 GABA(A)R in complex with GARLH4 and the Neuroligin2 transmembrane helix, in CL47a

Summary for 9RGE

Entry DOI	10.2210/pdb9rge/pdb
EMDB information	51521 53949
Descriptor	Gamma-aminobutyric acid receptor subunit alpha-1, [(2R)-2-octanoyloxy-3-[oxidanyl-[(1R,2R,3S,4R,5R,6S)-2,3,6-tris(oxidanyl)-4,5-diphosphonooxy-cyclohexyl]oxy-phosphoryl]oxy-propyl] octanoate, PALMITIC ACID, ... (18 entities in total)
Functional Keywords	gaba, neurotransmission, inhibitory synapse, protein complex, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	7
Total formula weight	275598.79
Authors	Kasaragod, V.B.,Aricescu, A.R. (deposition date: 2025-06-06, release date: 2026-06-17)
Primary citation	Kasaragod, V.B.,Aricescu, A.R. CryoEM structure of human alpha1beta3gamma2 GABA(A)R in complex with GARLH4 and the TMD of Neuroligin2, in CL47a To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.1 Å)

Structure validation