9RF2

M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography: ELF5

Summary for 9RF2

• Entry DOI: 10.2210/pdb9rf2/pdb
• Descriptor: Monoacylglycerol lipase, [1-[6-[(4-methoxyphenyl)amino]pyrimidin-4-yl]pyrazol-4-yl]-[(3S)-3-oxidanylpyrrolidin-1-yl]methanone, [1-[6-[(4-methoxyphenyl)amino]pyrimidin-4-yl]pyrazol-4-yl]-[(3R)-3-oxidanylpyrrolidin-1-yl]methanone, ... (5 entities in total)
• Functional Keywords: rv0183, inhibitor, monoacylglycerol lipase, hydrolase
• Biological source: Mycobacterium tuberculosis H37Rv
• Total number of polymer chains: 1
• Total formula weight: 34414.30

Authors

Riegler-Berket, L.,Goedl, L.,Oberer, M.,Polidori, N. (deposition date: 2025-06-04, release date: 2025-08-13)

• Primary citation: Riegler-Berket, L.,Goedl, L.,Oberer, M.,Polidori, N.; M. tuberculosis meets European Lead Factory: identification and structural characterization of novel Rv0183 inhibitors using X-ray crystallography; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.6 Å)