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9QXF

SARS-CoV-2 nsp14 with 5-chlorothiophene-2-sulfonamide

Summary for 9QXF
Entry DOI10.2210/pdb9qxf/pdb
DescriptorGuanine-N7 methyltransferase nsp14, GLYCEROL, 5-chloranylthiophene-2-sulfonamide, ... (8 entities in total)
Functional Keywordssars-cov-2, nsp14, fragment screening, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2
Total number of polymer chains1
Total formula weight60911.33
Authors
Shi, X.,Kozielski, F. (deposition date: 2025-04-15, release date: 2026-04-29)
Primary citationShi, X.,Wang, Q.,Dong, D.,Xu, M.,Al Busaidi, F.,Bowler, M.,Haider, S.,Kozielski, F.
Fragment-based screening reveals novel SARS-CoV-2 nsp14 targeting fragments.
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.25 Å)
Structure validation

254917

PDB entries from 2026-06-10

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