9QXB

SARS-CoV-2 nsp14 with N-methyl-1-(2-methyl-5-phenylpyrazol-3-yl)methanamine

Summary for 9QXB

• Entry DOI: 10.2210/pdb9qxb/pdb
• Descriptor: Guanine-N7 methyltransferase nsp14, methyl-3-methyl-5-phenyl-2H-pyrazol-4-methyl amine, DIMETHYL SULFOXIDE, ... (6 entities in total)
• Functional Keywords: sars-cov-2, nsp14, fragment screening, viral protein
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 1
• Total formula weight: 60431.33

Authors

Shi, X.,Kozielski, F. (deposition date: 2025-04-15, release date: 2026-04-29)

• Primary citation: Shi, X.,Wang, Q.,Dong, D.,Xu, M.,Al Busaidi, F.,Bowler, M.,Haider, S.,Kozielski, F.; Fragment-based screening reveals novel SARS-CoV-2 nsp14 targeting fragments.; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.84 Å)