9QUH

Structure of human MTH1 in complex with 8DG by MicroED using high electron fluence

Summary for 9QUH

• Entry DOI: 10.2210/pdb9quh/pdb
• Descriptor: 7,8-dihydro-8-oxoguanine triphosphatase, 8-OXO-2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, SULFATE ION, ... (4 entities in total)
• Functional Keywords: serial electron diffraction, serialed, microed, mth1, 8dg, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 37842.02

Authors

Hofer, G.,Wang, L.,Pacoste, L.,Hager, P.,Fonjallaz, A.,Scaletti Hutchinson, E.,Stenmark, P.,Di Palma, M.,Williams, L.,Worral, J.,Steiner, R.,Xu, H.,Zou, X. (deposition date: 2025-04-10, release date: 2026-04-22)

• Primary citation: Hofer, G.,Wang, L.,Pacoste, L.,Hager, P.,Fonjallaz, A.,Williams, L.,Worrall, J.,Steiner, R.,Xu, H.,Zou, X.; Continuous Serial Electron Diffraction for High Quality Protein Structures; To Be Published,

Experimental method

ELECTRON CRYSTALLOGRAPHY (2.32 Å)