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9QSW

Crystal structure of an NtA622L variant in complex with NADP+ and Nicotinic acid

Summary for 9QSW
Entry DOI10.2210/pdb9qsw/pdb
Related9QRG
DescriptorIsoflavone reductase homolog A622-like, NICOTINIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (4 entities in total)
Functional Keywordsoxidoreductase, nicotine, niacin, nadph, rossmann-fold, ifr-like, pip-reductase, plant protein
Biological sourceNicotiana tabacum (common tobacco)
Total number of polymer chains1
Total formula weight35507.25
Authors
Mokos, D.,Daniel, B. (deposition date: 2025-04-07, release date: 2026-04-15)
Primary citationMokos, D.,Leitner, D.,Schruefer, A.,Grubmueller, S.,Reisz, C.,Juric, J.,Berger, T.,Singh, A.,Friess, M.,Breinbauer, R.,Gruber, K.,Daniel, B.
A622: A key oxidoreductase in the Nicotine biosynthesis
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.68 Å)
Structure validation

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PDB entries from 2026-06-17

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