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9QRG

Crystal structure of mutant NtA622L in complex with NADP+ and Nicotinamide

Summary for 9QRG
Entry DOI10.2210/pdb9qrg/pdb
DescriptorIsoflavone reductase homolog A622-like, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, NICOTINAMIDE, ... (5 entities in total)
Functional Keywordsoxidoreductase, nicotine, niacin, nadph, rossmann-fold, ifr-like, pip-reductase, plant protein
Biological sourceNicotiana tabacum (common tobacco)
Total number of polymer chains1
Total formula weight35552.24
Authors
Mokos, D.,Daniel, B. (deposition date: 2025-04-03, release date: 2026-04-15)
Primary citationMokos, D.,Leitner, D.,Schruefer, A.,Grubmueller, S.,Reisz, C.,Juric, J.,Berger, T.,Singh, A.,Friess, M.,Breinbauer, R.,Gruber, K.,Daniel, B.
A622: A key oxidoreductase in the Nicotine biosynthesis
To Be Published,
Experimental method
X-RAY DIFFRACTION (1.3 Å)
Structure validation

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PDB entries from 2026-06-10

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