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9QRC

SARS-CoV-2 nsp14 with 6-methyl-2-[(4-methylphenyl)methyl]pyridazin-3-one

This is a non-PDB format compatible entry.
Summary for 9QRC
Entry DOI10.2210/pdb9qrc/pdb
DescriptorGuanine-N7 methyltransferase nsp14, 6-methyl-2-[(4-methylphenyl)methyl]pyridazin-3-one, DIMETHYL SULFOXIDE, ... (6 entities in total)
Functional Keywordssars-cov-2, nsp14, fragment screening, viral protein
Biological sourceSevere acute respiratory syndrome coronavirus 2
Total number of polymer chains1
Total formula weight60366.19
Authors
Shi, X.,Kozielski, F.,Wang, Q.,Dong, D. (deposition date: 2025-04-03, release date: 2026-04-15)
Primary citationShi, X.,Wang, Q.,Dong, D.,Xu, M.,Al Busaidi, F.,Bowler, M.,Haider, S.,Kozielski, F.
Fragment-based screening reveals novel SARS-CoV-2 nsp14 targeting fragments.
To Be Published,
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation

254917

PDB entries from 2026-06-10

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