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9QPO

CryoEM structure of human MATa2 in complex with MATBv2 at 2.6 A resolution

Summary for 9QPO
Entry DOI10.2210/pdb9qpo/pdb
EMDB information53276
DescriptorS-adenosylmethionine synthase isoform type-2, Isoform 2 of Methionine adenosyltransferase 2 subunit beta (3 entities in total)
Functional Keywordsmethylation, adomet, same, protein-protein complexes, transferase
Biological sourceHomo sapiens (human)
More
Total number of polymer chains7
Total formula weight287693.84
Authors
Khaja, F.,Antonyuk, S.V.,Muench, S.P.,Hasnain, S.S. (deposition date: 2025-03-27, release date: 2026-04-08)
Primary citationKhaja, F.,Vara, R.,Aspinall, L.P.,Merriman, C.,Maerivoet, A.,White, J.B.R.,Muench, S.P.,Hasnain, S.S.,Antonyuk, S.V.
High resolution cryoEM structures reveal allosteric regulation of the catalytic activity of the multi-protein human MAT enzyme complexes
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.6 Å)
Structure validation

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PDB entries from 2026-04-08

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