9QKQ

Crystal structure of hTEAD4 YAP binding domain (hTEAD4-YBD) in complex with peptide 6

Summary for 9QKQ

• Entry DOI: 10.2210/pdb9qkq/pdb
• Descriptor: Transcriptional enhancer factor TEF-3, peptide 6, 1,2-ETHANEDIOL, ... (6 entities in total)
• Functional Keywords: human tead4, yap binding domain, transcription
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 56880.29

Authors

Pozzi, C. (deposition date: 2025-03-20, release date: 2026-04-08)

• Primary citation: Malpezzi, G.,Scalvini, L.,Tagliazucchi, L.,Chiaravalle, A.,Aiello, D.,Saporito, G.,Illuminati, D.,Pacifico, S.,Lopresti, L.,Raucci, L.,Guerrini, R.,Pozzi, C.,Venturelli, A.,Ponterini, G.,Mor, M.,Costi, M.P.; Deciphering the structural and functional properties of interface 3 and lipidation pocket of hTEAD4 to develop new Hippo Pathway inhibitors through fluorescence anisotropy; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.74 Å)