9QJN

Cryo-EM structure of the human CAK bound to OTS964

Summary for 9QJN

• Entry DOI: 10.2210/pdb9qjn/pdb
• Related: 9QJJ
• EMDB information: 53205
• Descriptor: CDK-activating kinase assembly factor MAT1, Cyclin-H, Cyclin-dependent kinase 7, ... (5 entities in total)
• Functional Keywords: kinase, cyclin-dependent kinase, inhibitor, cell cycle
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 87711.15

Authors

McGeoch, A.J.S.,Cushing, V.I.,Cronin, N.B.,Alfieri, C.,Greber, B.J. (deposition date: 2025-03-19, release date: 2026-03-18)

• Primary citation: McGeoch, A.J.S.,Cushing, V.I.,Roumeliotis, T.I.,Cronin, N.B.,Alfieri, C.,Greber, B.J.,Choudhary, J.; Cryo-EM structures of the CDK11-cyclin L-SAP30BP complex reveal mechanisms of CDK11 regulation; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.4 Å)