9QDZ

GID4 in complex with Compound 14

This is a non-PDB format compatible entry.

Summary for 9QDZ

• Entry DOI: 10.2210/pdb9qdz/pdb
• Descriptor: Glucose-induced degradation protein 4 homolog, ~{N}-[3-fluoranyl-5-(5-methyl-4-piperidin-1-ylcarbonyl-furan-2-yl)phenyl]-4,4-dimethyl-piperidine-1-carboximidamide, GLYCEROL, ... (4 entities in total)
• Functional Keywords: e3 ubiquitin ligase, ubiquitination, targeted protein degradation, ligase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 20080.37

Authors

Pastok, M.W.,Gorecka-Minakowska, K.M.,Klejnot, M.,Skowron, A.N.,Wisniewski, J.,Walczak, M.J. (deposition date: 2025-03-07, release date: 2026-03-18)

• Primary citation: Pastok, M.W.,Gorecka-Minakowska, K.M.,Klejnot, M.,Skowron, A.N.,Wisniewski, J.,Walczak, M.J.; Novel chemical probes and conformational flexibility of GID4 - a substrate receptor of the Human CTLH E3 ligase complex; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.8 Å)