9QBM

X-ray structure of the drug binding domain of AlbA in complex with the KMR-04-177 compound of the pyrrolobenzodiazepines class

This is a non-PDB format compatible entry.

Summary for 9QBM

• Entry DOI: 10.2210/pdb9qbm/pdb
• Descriptor: Albicidin resistance protein, 4-[[(6~{S},6~{a}~{S})-2-methoxy-6-oxidanyl-11-oxidanylidene-5,6,6~{a},7,8,9-hexahydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]butanamide, 4-[[(6~{a}~{S})-2-methoxy-11-oxidanylidene-6~{a},7,8,9-tetrahydropyrrolo[2,1-c][1,4]benzodiazepin-3-yl]oxy]-~{N}-[4-(4-methylpiperazin-1-yl)phenyl]butanamide, ... (6 entities in total)
• Functional Keywords: drug binding, bacterial resistance, pyrrolobenzodiazepines, dna binding protein, antimicrobial protein
• Biological source: Klebsiella oxytoca
• Total number of polymer chains: 3
• Total formula weight: 81904.40

Authors

Di Palma, M.,Steiner, R.A. (deposition date: 2025-03-03, release date: 2026-03-11)

• Primary citation: Di Palma, M.,Steiner, R.A.; X-ray structure of the drug binding domain of AlbA in complex with the KMR-04-177 compound of the pyrrolobenzodiazepines class; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.95 Å)