9Q9C

Protein kinase CK2 catalytic subunit alpha' (CSNK2A2 gene product) in complex with F2X-Entry screen fragment D04

Summary for 9Q9C

Entry DOI	10.2210/pdb9q9c/pdb
Descriptor	Casein kinase II subunit alpha', methyl 4-fluoro-D-phenylalaninate, 1,2-ETHANEDIOL, ... (4 entities in total)
Functional Keywords	fragment-based screening, protein kinase ck2, casein kinase ii, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	43691.81
Authors	Werner, C.,Harasimowicz, H.,Barthel, T.,Weiss, M.S.,Niefind, K. (deposition date: 2025-02-26, release date: 2026-01-14)
Primary citation	Werner, C.,Barthel, T.,Harasimowicz, H.,Marminon, C.,Weiss, M.S.,Borgne, M.L.,Niefind, K. Crystallographic Fragment Screening with CK2 alpha', an Isoform of Human Protein Kinase CK2 Catalytic Subunit, and Its Use to Obtain a CK2 alpha'/Heparin Complex Structure Kinases Phosphatases, 4:1-, 2026 Cited by DOI: 10.3390/kinasesphosphatases4010001 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.66 Å)

Structure validation