9Q7Y

Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (365) Complex Bound by the MEDI3622 Fab

Summary for 9Q7Y

• Entry DOI: 10.2210/pdb9q7y/pdb
• EMDB information: 72319
• Descriptor: Inactive rhomboid protein 1, MEDI3622 Fab Light Chain, MEDI3622 Fab Heavy Chain, ... (8 entities in total)
• Functional Keywords: complex, membrane protein, enzyme, adam, rhomboid
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 4
• Total formula weight: 155277.31

Authors

Seegar, T.M.,Maciag, J.J.,Ungvary, J.N. (deposition date: 2025-08-25, release date: 2026-04-01)

• Primary citation: Seegar, T.M.,Maciag, J.J.,Ungvary, J.N.; Zymogen ADAM17- iRhom1 Cytoplasmic Deletion (365) Complex Bound by the MEDI3622 Fab; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.35 Å)