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9Q7P

Solution Structure of the Beta Domain of Human MT1A Bound to 6 Cu(I) Ions

Summary for 9Q7P
Entry DOI10.2210/pdb9q7p/pdb
NMR InformationBMRB: 31267
DescriptorImmunoglobulin G-binding protein G, Metallothionein-1A fusion,Metallothionein-1A, COPPER (I) ION (2 entities in total)
Functional Keywordscu homeostasis, cu-thiolate cluster, metal-dependent fold, metal storage, metal binding protein
Biological sourceHomo sapiens (human)
More
Total number of polymer chains1
Total formula weight9965.01
Authors
Melenbacher, A.,Rintala-Dempsey, A.C.,Shaw, G.S.,Stillman, M.J. (deposition date: 2025-08-25, release date: 2026-08-05)
Primary citationMelenbacher, A.,Rintala-Dempsey, A.C.,Liu, L.,Chang, L.,Shaw, G.S.,Stillman, M.J.
The NMR structure of human Cu6-B MT1 reveals that the Cu6S9 binding site adopts a ladder structure not the closed prism structure of inorganic Cu(I)-thiolate compounds
To Be Published,
Experimental method
SOLUTION NMR
Structure validation

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PDB entries from 2026-11-11

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