9Q3U

Cryo EM structure of elk ACE2 in complex with SARS-CoV-2 spike trimer

Summary for 9Q3U

Entry DOI	10.2210/pdb9q3u/pdb
Related	9Q3V
EMDB information	72207
Descriptor	Angiotensin-converting enzyme 2, Spike protein, 2-acetamido-2-deoxy-beta-D-glucopyranose (3 entities in total)
Functional Keywords	sars-cov-2, cervidae, ace2 receptor, viral host interaction, host susceptibility, viral protein
Biological source	Cervus canadensis More
Total number of polymer chains	4
Total formula weight	505612.63
Authors	Ye, K.,Tao, Y.J.,Wan, X.F. (deposition date: 2025-08-19, release date: 2026-02-25)
Primary citation	Espada, C.,Ye, K.,Long, Y.,Pasai, K.,DeLiberto, T.J.,Heale, J.,Wiese, R.,Yang, Q.,Zhou, M.,Streich, S.,Tao, Y.J.,Chandler, J.C.,Wan, X.F. Species- and variant-specific ACE2 compatibility shapes SARS-CoV-2 spillover potential in North American cervids To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.37 Å)

Structure validation