9Q1L

Crystal structure of the walnut allergen Jug r 2 bound to the human-derived Fab 6D12

Summary for 9Q1L

• Entry DOI: 10.2210/pdb9q1l/pdb
• Descriptor: 6D12 Fab light chain, 6D12 Fab Heavy Chain, Vicilin Jug r 2.0102 hairpinin alpha 4, ... (6 entities in total)
• Functional Keywords: walnut, allergen, antibody binding, fab, vicilin, alpha-hairpinin domains, seed storage protein, allergen-immune system complex, allergen/immune system
• Biological source: Homo sapiens; More
• Total number of polymer chains: 6
• Total formula weight: 108616.31

Authors

Pedersen, L.C.,Lytle, I.R.,Mueller, G.A.,Croote, D.C. (deposition date: 2025-08-14, release date: 2026-01-21)

• Primary citation: Leighton, G.O.,Cosey, T.M.,De Diavoukana, E.R.,Lytle, I.R.,Foo, A.C.Y.,Pedersen, L.C.,Gabel, S.A.,Petrovich, R.M.,Shi, M.,Aruva, V.,Creeks, P.,Wong, J.J.W.,Zhang, J.,Peebles Jr., R.S.,Croote, D.,Smith, S.A.,Mueller, G.A.; Polymeric alpha-Hairpinin Allergens Induce a Functional Response via a Single Antibody.; Allergy, 2025; PubMed: 41476027; DOI: 10.1111/all.70201

Experimental method

X-RAY DIFFRACTION (1.56 Å)