9Q0S

JCN037 in complex with wild-type EGFR

Summary for 9Q0S

Entry DOI	10.2210/pdb9q0s/pdb
Descriptor	Epidermal growth factor receptor, N-(3-bromo-2-fluorophenyl)-7,8-dihydro[1,4]dioxino[2,3-g]quinazolin-4-amine (3 entities in total)
Functional Keywords	cancer, drug discovery, transferase
Biological source	Homo sapiens (human)
Total number of polymer chains	1
Total formula weight	37680.31
Authors	Lantry, A.M.,Abidakun, O.A.,Heppner, D.E. (deposition date: 2025-08-13, release date: 2025-12-10)
Primary citation	Lantry, A.M.,Abidakun, O.A.,Heppner, D.E. Structural and functional studies of EGFR inhibitor To Be Published,
Experimental method	X-RAY DIFFRACTION (2.46 Å)

Structure validation