9PXD

M20A Mutant of E. coli Dihydrofolate Reductase Complexed with Folate and Nicotinamide Adenine Dinucleotide Phosphate (oxidized form)

Summary for 9PXD

• Entry DOI: 10.2210/pdb9pxd/pdb
• Descriptor: Dihydrofolate reductase, FOLIC ACID, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
• Functional Keywords: m20a, dhfr, oxidoreductase, nadp+, folate
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 19466.71

Authors

Fried, S.D.E.,Mathews, I.I.,Boxer, S.G. (deposition date: 2025-08-05, release date: 2026-08-26)

• Primary citation: Fried, S.D.E.,Mukherjee, S.,Boxer, S.G.; Role of Electrostatics in Hydride Transfer by Dihydrofolate Reductase; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.07 Å)