9PXC

Y100F Mutant of E. coli Dihydrofolate Reductase Complexed with NADP+ (oxidized form)

Summary for 9PXC

• Entry DOI: 10.2210/pdb9pxc/pdb
• Descriptor: Dihydrofolate reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, CALCIUM ION, ... (4 entities in total)
• Functional Keywords: y100f, dhfr, oxidoreductase
• Biological source: Escherichia coli
• Total number of polymer chains: 1
• Total formula weight: 18786.82

Authors

Fried, S.D.E.,Mathews, I.I.,Boxer, S.G. (deposition date: 2025-08-05, release date: 2025-09-03)

• Primary citation: Fried, S.D.E.,Mukherjee, S.,Boxer, S.G.; Role of Electrostatics in Hydride Transfer by Dihydrofolate Reductase; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.37 Å)