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9PW3

Cryo-EM structure of renal amyloid fibril from a variant apolipoprotein A-I R173P amyloidosis patient

Summary for 9PW3
Entry DOI10.2210/pdb9pw3/pdb
EMDB information71896 71897 71898
DescriptorApolipoprotein A-I (1 entity in total)
Functional Keywordsapolipoprotein a-i, aapoai, r173p, kidney, amyloidosis., protein fibril
Biological sourceHomo sapiens (human)
Total number of polymer chains10
Total formula weight281206.37
Authors
Nguyen, B.A.,Saelices, L. (deposition date: 2025-08-04, release date: 2026-03-18)
Primary citationNguyen, B.A.,Saelices, L.
Structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations, revealed by cryo-EM
To Be Published,
Experimental method
ELECTRON MICROSCOPY (2.73 Å)
Structure validation

250835

PDB entries from 2026-03-18

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