9PVZ

Cryo-EM structure of cardiac amyloid fibril from a variant apolipoprotein A-I R173P amyloidosis patient

Summary for 9PVZ

• Entry DOI: 10.2210/pdb9pvz/pdb
• Related: 9PVY
• EMDB information: 71896 71897
• Descriptor: Apolipoprotein A-I (1 entity in total)
• Functional Keywords: apolipoprotein a-i, aapoai, r173p, cardiac, amyloidosis., protein fibril
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 10
• Total formula weight: 281206.37

Authors

Nguyen, B.A.,Saelices, L. (deposition date: 2025-08-04, release date: 2026-03-18)

• Primary citation: Nguyen, B.A.,Saelices, L.; Structural variability of apolipoprotein A-I amyloid fibrils across organs, mutations, and clinical presentations, revealed by cryo-EM; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.3 Å)