9PVL

Crystal Structure of Fluorophore-binding Protein JF657-bp

Summary for 9PVL

Entry DOI	10.2210/pdb9pvl/pdb
Descriptor	JF657-bp, 2-{2-[2-(2-{2-[2-(2-ETHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, CALCIUM ION, ... (5 entities in total)
Functional Keywords	de novo designed protein, small molecule binder, fluorophore-binding, de novo protein, multiplex imaging
Biological source	synthetic construct
Total number of polymer chains	4
Total formula weight	63885.47
Authors	Bera, A.K.,Tran, L.,An, L.,Baker, D. (deposition date: 2025-08-01, release date: 2026-07-15, Last modification date: 2026-07-22)
Primary citation	Tran, L.,Klein, S.,Juergens, D.,Sharma, S.,Decarreau, J.,Lee, G.R.,Wang, Y.,Chen, W.,Bera, A.K.,Kang, A.,Woods, J.,Joyce, E.,Vafeados, D.K.,Roullier, N.,Li, X.,Liu, B.,Bo, Y.,Muratspahic, E.,Brown, T.A.,Grimm, J.B.,Patel, R.,Lavis, L.D.,Mahamid, J.,An, L.,Baker, D. De novo design of orthogonal far-red, orange, and green fluorophore-binding proteins for multiplexed imaging Science, 2026 Cited by DOI: 10.1126/science.aeb0822 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.44 Å)

Structure validation