9PUW

Insulin Receptor bound to Ins-AC-S2

Summary for 9PUW

• Entry DOI: 10.2210/pdb9puw/pdb
• EMDB information: 71878
• Descriptor: Isoform Long of Insulin receptor, Ins-AC-S2 chain A, Insulin chain B (3 entities in total)
• Functional Keywords: antagonist, receptor tyrosine kinase, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 455616.25

Authors

Vogel, A.,Hill, C.P.,Blakely, A. (deposition date: 2025-07-31, release date: 2026-06-10)

• Primary citation: Vogel, A.,Blakely, A.,Dao, Y.,Lin, N.P.,Chou, D.,Hill, C.P.; Structural basis of insulin receptor antagonism by bivalent site 1-site 2 ligands; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.64 Å)