9PSL

Co-crystal structure of BAF60A (SMARCD1) in complex with PU.1 peptide

Summary for 9PSL

• Entry DOI: 10.2210/pdb9psl/pdb
• Descriptor: SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1, Transcription factor PU.1, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: pu.1, spi1, ets transcription factor, ppi, protein-protein interaction, baf, baf subunit, yeats-like domain, mammalian mswi/snf, chromatin remodeling, gene regulation
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 128115.57

Authors

Clasman, J.C.,Sadalge, D.S.,Von der Porten, L.,Wu, S.,Nelen, M.,Davenport, Y.W.,Bellon, S.F.,Taherbhoy, A.M. (deposition date: 2025-07-25, release date: 2026-08-05)

• Primary citation: Sadalge, D.S.,Clasman, J.R.,Topal, S.,Musser, D.,Von der Porten, L.,Wu, S.,Schultz, S.,Austin, W.,Huang, D.,Setser, J.W.,Martinez, M.R.,Kiselar, J.,Hesler, S.,Blevins, S.J.,Turegun, B.,Palowitch, G.M.,Khalil, A.,Pulice, J.L.,Chance, M.R.,Wilson, K.J.,Nelen, M.,Lahr, D.,Sandoval, G.J.,Davenport, Y.W.,Bellon, S.F.,Taherbhoy, A.M.; Structural and functional basis of PU.1-BAF interaction enables targeting of lineage-specific transcription; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.39 Å)