9PPX

CryoEM structure of delta opioid receptor bound to G proteins and naltrexone

Summary for 9PPX

Entry DOI	10.2210/pdb9ppx/pdb
EMDB information	71777
Descriptor	Delta-type opioid receptor, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (6 entities in total)
Functional Keywords	gpcr, delta opioid receptor, membrane protein
Biological source	Homo sapiens (human) More
Total number of polymer chains	5
Total formula weight	146302.50
Authors	Fay, J.F.,Che, T. (deposition date: 2025-07-22, release date: 2026-03-04)
Primary citation	Bernhard, S.M.,Roy Chowdhury, S.,Murata, T.,Reinl, E.L.,Ramos-Gonzalez, N.,Denn, E.,Appourchaux, K.,Inoue, A.,England, S.K.,Fay, J.F.,Majumdar, S.,Chanda, B.,Che, T. Mechanistic Insights into the Therapeutic Properties of Delta Opioid Receptor To Be Published,
Experimental method	ELECTRON MICROSCOPY (3.04 Å)

Structure validation