9PNX

Crystal structure of anti-IL2Rgamma VH3-20 domain

Summary for 9PNX

• Entry DOI: 10.2210/pdb9pnx/pdb
• Descriptor: anti-IL2Rgamma VH3-20 domain, CALCIUM ION (3 entities in total)
• Functional Keywords: computational design, vh, antibody, germline, immune system
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 1
• Total formula weight: 13898.39

Authors

Theiker, D.,Hanna, J.,Hong, G.,Walters, P.,Capodagli, G.,Buetz-Duncan, C.,Carnevale, C.,Sereno, A.,Karow, M.,Chaie, F.,Lin, A.,Pigott, C.R.,Kang, J.,Gallo, M.,Sharma, R.,Del Cid, N.,Nicely, N.I.,Kuhlman, B.,Demarest, S.J. (deposition date: 2025-07-21, release date: 2026-07-22)

• Primary citation: Theiker, D.,Hanna, J.,Hong, G.,Walters, P.,Capodagli, G.,Buetz-Duncan, C.,Carnevale, C.,Sereno, A.,Karow, M.,Chaie, F.,Lin, A.,Pigott, C.R.,Kang, J.,Gallo, M.,Sharma, R.,Del Cid, N.,Nicely, N.I.,Kuhlman, B.,Demarest, S.J.; Computational Design of the Functional Human VH Germline Repertoire to Enable Conditional Multi-Specific Therapeutic Development; To Be Published,

Experimental method

X-RAY DIFFRACTION (1.35 Å)