9PNN

Cryo-EM structure of J601-A6 Fab in complex with HIV-1 BG505 DS-SOSIP Env trimer

Summary for 9PNN

• Entry DOI: 10.2210/pdb9pnn/pdb
• EMDB information: 71767
• Descriptor: Envelope glycoprotein BG505 DS-SOSIP gp41, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (11 entities in total)
• Functional Keywords: antibody-antigen complex, fusion peptide directed, viral surface glycoprotein, antiviral protein, viral protein-immune system complex, viral protein/immune system
• Biological source: Human immunodeficiency virus 1; More
• Total number of polymer chains: 12
• Total formula weight: 388173.74

Authors

Wang, S.,Zhou, T.,Kwong, P.D.,Morano, N.C.,Shapiro, L. (deposition date: 2025-07-21, release date: 2025-12-17)

• Primary citation: Duan, H.,Nkolola, J.P.,Wang, S.,Kwong, P.D.,Barouch, D.H.,Zhou, T.; Dual Vaccine Elicitation of HIV-1 Neutralizing Antibodies against V2 Apex and Fusion Peptide; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.5 Å)