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9PNI

Cryo-EM structure of J601-1B2 Fab in complex with HIV-1 BG505 DS-SOSIP Env trimer

Summary for 9PNI
Entry DOI10.2210/pdb9pni/pdb
EMDB information71766
DescriptorEnvelope glycoprotein BG505 DS-SOSIP gp41, 2-acetamido-2-deoxy-beta-D-glucopyranose, alpha-D-mannopyranose, ... (11 entities in total)
Functional Keywordsantibody-antigen complex, fusion peptide directed, viral surface glycoprotein, antiviral protein, viral protein-immune system complex, viral protein/immune system
Biological sourceHuman immunodeficiency virus 1
More
Total number of polymer chains12
Total formula weight386902.60
Authors
Wang, S.,Zhou, T.,Kwong, P.D. (deposition date: 2025-07-21, release date: 2025-12-17)
Primary citationDuan, H.,Nkolola, J.P.,Wang, S.,Kwong, P.D.,Barouch, D.H.,Zhou, T.
Dual Vaccine Elicitation of HIV-1 Neutralizing Antibodies against V2 Apex and Fusion Peptide
To Be Published,
Experimental method
ELECTRON MICROSCOPY (3.83 Å)
Structure validation

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