9PMS

Epitope editing of CD90 protects hematopoietic stem cells from immunotherapy and enables targeted enrichment for gene therapy

Summary for 9PMS

• Entry DOI: 10.2210/pdb9pms/pdb
• EMDB information: 71742
• Descriptor: Antibody heavy chain, Antibody light chain, Thy-1 membrane glycoprotein, ... (6 entities in total)
• Functional Keywords: antibody, antigen, complex, antitumor protein
• Biological source: Mus musculus (mouse); More
• Total number of polymer chains: 5
• Total formula weight: 106313.24

Authors

Choo, S.,Radtke, S.,Rupert, P.B.,Tong, A.H.,Swing, K.,Repele, A.,Starrs, M.,Humphreys, T.,Darari, A.,Strong, R.K.,Keim, H.P. (deposition date: 2025-07-18, release date: 2026-07-22)

• Primary citation: Choo, S.,Radtke, S.,Rupert, P.B.,Tong, A.H.,Swing, K.,Repele, A.,Starrs, M.,Humphreys, T.,Darari, A.,Strong, R.K.,Keim, H.P.; Epitope editing of CD90 protects hematopoietic stem cells from immunotherapy and enables targeted enrichment for gene therapy; To Be Published,

Experimental method

ELECTRON MICROSCOPY (3.56 Å)