9PLY

Crystal structure of the human DCAF1 WDR domain in complex with OICR-40156

This is a non-PDB format compatible entry.

Summary for 9PLY

• Entry DOI: 10.2210/pdb9ply/pdb
• Descriptor: DDB1- and CUL4-associated factor 1, (4P)-N-[(1S)-3-amino-1-(3-chloro-4-fluorophenyl)-3-oxopropyl]-4-(4-chloro-2-fluorophenyl)-5-{(1E)-3-[(3-methoxypropyl)amino]-3-oxoprop-1-en-1-yl}-1H-pyrrole-3-carboxamide, 1,2-ETHANEDIOL, ... (5 entities in total)
• Functional Keywords: transferase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 72468.87

Authors

Kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Krausser, C.,Wilson, B.,Al-awar, R.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC) (deposition date: 2025-07-16, release date: 2025-07-30)

• Primary citation: Kimani, S.,Dong, A.,Li, Y.,Seitova, A.,Krausser, C.,Wilson, B.,Al-awar, R.,Ackloo, S.,Arrowsmith, C.H.,Edwards, A.M.,Halabelian, L.,Structural Genomics Consortium (SGC); Crystal structure of the human DCAF1 WDR domain in complex with OICR-40156; To be published,

Experimental method

X-RAY DIFFRACTION (1.4 Å)