9PLR

CryoEM reconstruction of HUWE1-USP7 complex in the closed state

This is a non-PDB format compatible entry.

Summary for 9PLR

• Entry DOI: 10.2210/pdb9plr/pdb
• EMDB information: 71721
• Descriptor: E3 ubiquitin-protein ligase HUWE1, Ubiquitin carboxyl-terminal hydrolase 7 (2 entities in total)
• Functional Keywords: complex, e3-ligase-dub, ligase
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 2
• Total formula weight: 610897.17

Authors

Yatskevich, S.,Juszkiewicz, S. (deposition date: 2025-07-16, release date: 2026-07-22)

• Primary citation: Yatskevich, S.; Molecular mechanism of HUWE1-HAPSTR1-USP7-mediated ubiquitin chain amplification on nuclear proteins; To Be Published,

Experimental method

ELECTRON MICROSCOPY (2.88 Å)