9PJA

Cryo-EM structure of human NXPE1

Summary for 9PJA

• Entry DOI: 10.2210/pdb9pja/pdb
• EMDB information: 71685
• Descriptor: NXPE family member 1, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETYL COENZYME *A, ... (4 entities in total)
• Functional Keywords: sialic acid, acetyltransferase, hydrolase
• Biological source: Homo sapiens (human)
• Total number of polymer chains: 2
• Total formula weight: 129655.29

Authors

Zhang, H.,Li, F.,Piper, D.,Min, X. (deposition date: 2025-07-12, release date: 2026-06-03)

• Primary citation: Zhang, H.,Li, F.,Zhang, M.,Konno, H.,Yu, W.,Min, X.,Paulchakrabarti, M.,Choudhury, B.,Simons, A.,Piper, D.,Hsu, H.,Ouyang, W.; Structure and function of human NXPE1, a sialic acid O-acetyltransferase; Biorxiv, 2026; DOI: 10.64898/2026.05.20.726592

Experimental method

ELECTRON MICROSCOPY (2.8 Å)