9PHY

AshA from Amycolatopsis keratiniphila, an actinothioneine-biosynthetic sulfoxide synthase in complex with histidine

Summary for 9PHY

Entry DOI	10.2210/pdb9phy/pdb
Descriptor	Sulfoxide synthase AshA, FE (III) ION, HISTIDINE, ... (5 entities in total)
Functional Keywords	actinothioneine, sulfoxide synthase, histidine, cysteine, nonheme iron, oxidoreductase
Biological source	Amycolatopsis keratiniphila
Total number of polymer chains	1
Total formula weight	86371.27
Authors	Ireland, K.A.,Davis, K.M. (deposition date: 2025-07-09, release date: 2026-10-14)
Primary citation	Abbott, M.L.,Leeman, J.T.,Kayrouz, C.M.,Ireland, K.A.,Davis, K.M.,Seyedsayamdost, M.R. Widespread Biosynthesis of Thiohistidine Dipeptides in Bacteria J.Am.Chem.Soc., 2026 Cited by DOI: 10.1021/jacs.6c03714 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.11 Å)

Structure validation