9PH9

Crystal structure of SARS-CoV-2 nsp14 with SAH and GpppA bound

Summary for 9PH9

• Entry DOI: 10.2210/pdb9ph9/pdb
• Descriptor: Guanine-N7 methyltransferase nsp14, ZINC ION, GUANOSINE-P3-ADENOSINE-5',5'-TRIPHOSPHATE, ... (7 entities in total)
• Functional Keywords: methyltransferase sars-cov-2 rna modification, transferase
• Biological source: Severe acute respiratory syndrome coronavirus 2
• Total number of polymer chains: 2
• Total formula weight: 123475.60

Authors

Caputo, A.T.,Dennis, M.L.,Blackman, L.D. (deposition date: 2025-07-08, release date: 2026-07-15)

• Primary citation: Guan, D.; Predictive deep learning and active learning identifies compounds targeting SARS-CoV-2 non-structural protein nsp14; To Be Published,

Experimental method

X-RAY DIFFRACTION (2.257 Å)