9PDG

Three-dimensional structure of kinase inhibitor Palbociclib-HIV TAR complex

Summary for 9PDG

• Entry DOI: 10.2210/pdb9pdg/pdb
• NMR Information: BMRB: 31259
• Descriptor: RNA (29-MER), 6-ACETYL-8-CYCLOPENTYL-5-METHYL-2-[(5-PIPERAZIN-1-YLPYRIDIN-2-YL)AMINO]PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE (2 entities in total)
• Functional Keywords: palbociclib, complex, hiv-1 tar, rna, small molecule-rna complex
• Biological source: synthetic construct
• Total number of polymer chains: 1
• Total formula weight: 9757.10

Authors

Ramireddy, R.R.,Vidadala, V.N.,Chaubey, B.,Olsen, G.,Varani, G. (deposition date: 2025-06-30, release date: 2026-02-04)

• Primary citation: Ramireddy, R.R.,Vidadala, V.N.,Chaubey, B.,Olsen, G.,Varani, G.; Three-dimensional structure of kinase inhibitor Palbociclib-HIV TAR complex; To Be Published,

Experimental method

SOLUTION NMR