9P3Q

Zebrafish TRPM5 D797A mutant with 5mM calcium

Summary for 9P3Q

• Entry DOI: 10.2210/pdb9p3q/pdb
• EMDB information: 71251
• Descriptor: Transient receptor potential cation channel subfamily M member 5, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION (3 entities in total)
• Functional Keywords: trpm5 channel; ion channel; cation channel; sodium channel; calcium; cbta, transport protein
• Biological source: Danio rerio (zebrafish)
• Total number of polymer chains: 4
• Total formula weight: 490238.77

Authors

Ruan, Z.,Du, J.,Lu, W. (deposition date: 2025-06-14, release date: 2026-01-07)

• Primary citation: Ruan, Z.,Du, J.,Lu, W.; A single allosteric site merges activation, modulation and inhibition in TRPM5; Nat.Chem.Biol., 2026; DOI: 10.1038/s41589-025-02097-7

Experimental method

ELECTRON MICROSCOPY (3.5 Å)