9P3N

The open state of zebrafish TRPM5 with 1mM EDTA and 0.5mM CBTA

This is a non-PDB format compatible entry.

Summary for 9P3N

• Entry DOI: 10.2210/pdb9p3n/pdb
• EMDB information: 71245
• Descriptor: Green fluorescent protein,Transient receptor potential cation channel subfamily M member 5, CALCIUM ION, (2R)-2-(hydroxymethyl)-4-{[(25R)-10alpha,14beta,17beta-spirost-5-en-3beta-yl]oxy}butyl 4-O-alpha-D-glucopyranosyl-beta-D-glucopyranoside, ... (5 entities in total)
• Functional Keywords: trpm5 channel; ion channel; cation channel; sodium channel; calcium; cbta, transport protein
• Biological source: Danio rerio (zebrafish); More
• Total number of polymer chains: 4
• Total formula weight: 673710.53

Authors

Ruan, Z.,Du, J.,Lu, W. (deposition date: 2025-06-14, release date: 2026-01-07)

• Primary citation: Ruan, Z.,Du, J.,Lu, W.; A single allosteric site merges activation, modulation and inhibition in TRPM5; Nat.Chem.Biol., 2026; DOI: 10.1038/s41589-025-02097-7

Experimental method

ELECTRON MICROSCOPY (3.5 Å)