9P2U

Structure of radical S-adenosylmethionine methyltransferase, NocN, from Nocardia with two AzaSAM and [4Fe-4S] cluster bound

Summary for 9P2U

Entry DOI	10.2210/pdb9p2u/pdb
Descriptor	Radical S-adenosylmethionine methyltransferase NocN, S-5'-AZAMETHIONINE-5'-DEOXYADENOSINE, IRON/SULFUR CLUSTER, ... (4 entities in total)
Functional Keywords	radical s-adenosylmethionine enzyme nocathiacin nosiheptide, oxidoreductase
Biological source	Nocardia sp. ATCC 202099
Total number of polymer chains	1
Total formula weight	47491.97
Authors	Wang, B.,Knox, H.L.,York, N.J.,Radle, M.I.,Silakov, A.,Booker, S.J. (deposition date: 2025-06-12, release date: 2026-06-03)
Primary citation	Wang, B.,Knox, H.L.,York, N.J.,Radle, M.I.,Silakov, A.,Booker, S.J. Structural and Spectroscopic Basis for Catalysis by a Class C Radical S-Adenosylmethionine Methylase Involved in Nosiheptide/Nocathiacin Biosynthesis J.Am.Chem.Soc., 2026 Cited by DOI: 10.1021/jacs.6c03999 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation